I really liked Afro Samurai.
Full Meta Alchemist is my favorite because of the questions it brings up : Humanity, value of life and science, and "playing god."
Avatar: The Last Airbender - While not considered...japanese anime, it's still anime is spirit, and very epic in my opinion.
Serial Experiments Lain
Ergo Proxy
Ghost in the Shell
Cowboy Bebop
Trigun
Rurouni Kenshin
YuYu Hakusho
DragonBall Z (Still, hands down, the MOST epic anime ever created)
Various episodes in the Animatrix (such as the film noir style one)

Naruto is total garbage. Bleach is better but the same format.

__________________